Pediatric intestinal obstruction in Malawi: characteristics and outcomes

Am J Surg. 2016 Apr;211(4):722-6. doi: 10.1016/j.amjsurg.2015.11.024. Epub 2016 Jan 6.

Abstract

Background: Intestinal obstruction (IO) is a common pediatric surgical emergency in sub-Saharan Africa with high morbidity and mortality, but little is known about its etiopathogenesis in Malawi.

Methods: Retrospective analysis of patients seen from February 2012 to June 2014 at Kamuzu Central Hospital in Lilongwe, Malawi (n = 3,407). Pediatric patients with IO were analyzed (n = 130).

Results: Overall, 57% of patients were male with a mean age of 3.5 ± 4.1 years. A total of 52% of patients underwent operative intervention. The overall mortality rate was 3%. Leading causes of IO were Hirschprung's 29%, anorectal malformation 18%, and intussusception 4%. Neonates and patients with congenital causes of IO underwent surgery less frequently than infants and/or children and patients with acquired causes, respectively. These groups also demonstrated increased number of days from admission to surgery.

Conclusions: Increasing pediatric-specific surgical education and/or training and expanding access to resources may improve mortality after IO in poor medical communities within sub-Saharan Africa.

Keywords: Hirschprung's disease; Imperforate anus; Intussusception; Malawi; Obstruction; Pediatric surgery.

MeSH terms

  • Child, Preschool
  • Digestive System Surgical Procedures / methods*
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Intestinal Obstruction / epidemiology*
  • Intestinal Obstruction / etiology
  • Intestinal Obstruction / mortality
  • Intestinal Obstruction / surgery*
  • Length of Stay / statistics & numerical data
  • Malawi / epidemiology
  • Male
  • Retrospective Studies
  • Treatment Outcome