Guideline-Concordant Versus Discordant Antimicrobial Therapy in Patients With Community-Onset Complicated Intra-abdominal Infections

Infect Control Hosp Epidemiol. 2016 Jul;37(7):855-8. doi: 10.1017/ice.2016.64. Epub 2016 Mar 29.

Abstract

Overall IDSA/SIS intra-abdominal infection guideline compliance was not associated with improved outcomes; however, there was a longer time to active therapy (P=.024) and higher mortality (P=.077) if empiric therapy was too narrow per guidelines. These findings support the need for the implementation of customized institutional guidelines adapted from the IDSA/SIS guidelines. Infect Control Hosp Epidemiol 2016;37:855-858.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Anti-Infective Agents / therapeutic use*
  • Community-Acquired Infections / drug therapy
  • Community-Acquired Infections / microbiology
  • Community-Acquired Infections / mortality
  • Cross Infection / drug therapy
  • Cross Infection / mortality
  • Guideline Adherence / statistics & numerical data*
  • Humans
  • Intraabdominal Infections / drug therapy*
  • Intraabdominal Infections / microbiology
  • Intraabdominal Infections / mortality
  • Middle Aged
  • Practice Guidelines as Topic
  • Retrospective Studies
  • Treatment Outcome

Substances

  • Anti-Infective Agents