Comparative Epidemiology and Outcomes of Human Immunodeficiency virus (HIV), Non-HIV Non-transplant, and Solid Organ Transplant Associated Cryptococcosis: A Population-Based Study

Clin Infect Dis. 2018 Feb 1;66(4):608-611. doi: 10.1093/cid/cix867.

Abstract

In this population-based study in the contemporary era in the United States, the proportion of human immunodeficiency virus (HIV)-negative patients with cryptococcosis approaches that in HIV-infected patients. Cryptococcosis is associated with higher mortality rates in HIV-negative patients (including organ transplant recipients).

Keywords: Comparative epidemiology; crypto- coccosis; outcomes.

Publication types

  • Comparative Study
  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Antifungal Agents / therapeutic use
  • Cryptococcosis / epidemiology*
  • Cryptococcosis / mortality*
  • Female
  • HIV Infections / complications
  • HIV Infections / epidemiology*
  • Humans
  • Male
  • Meningitis, Cryptococcal
  • Middle Aged
  • Organ Transplantation / adverse effects*
  • Population Health*
  • Retrospective Studies
  • Transplant Recipients
  • United States / epidemiology
  • Young Adult

Substances

  • Antifungal Agents