Maternal and Fetal Outcomes Among Pregnant Women With Human Monkeypox Infection in the Democratic Republic of Congo

J Infect Dis. 2017 Oct 17;216(7):824-828. doi: 10.1093/infdis/jix260.

Abstract

Human monkeypox is an endemic disease in rain-forested regions of central Democratic Republic of Congo. We report fetal outcomes for 1 of 4 pregnant women who participated in an observational study at the General Hospital of Kole (Sankuru Province), where 222 symptomatic subjects were followed between 2007 and 2011. Of the 4 pregnant women, 1 gave birth to a healthy infant, 2 had miscarriages in the first trimester, and 1 had fetal death, with the macerated stillborn showing diffuse cutaneous maculopapillary skin lesions involving the head, trunk and extremities, including palms of hands and soles of feet.

Keywords: Democratic Republic of Congo; Monkeypox; abortion; maternal-fetal infection; orthopoxvirus; pregnancy.

Publication types

  • Case Reports
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Abortion, Spontaneous / virology
  • Adult
  • Democratic Republic of the Congo / epidemiology
  • Female
  • Humans
  • Monkeypox virus / isolation & purification*
  • Mpox (monkeypox) / epidemiology*
  • Mpox (monkeypox) / pathology*
  • Pregnancy
  • Pregnancy Complications, Infectious / epidemiology*
  • Pregnancy Complications, Infectious / virology*
  • Pregnancy Outcome*
  • Viral Load
  • Young Adult