Patch testing with a mixture of 2 phenol-formaldehyde resins

Contact Dermatitis. 1988 Aug;19(2):116-9. doi: 10.1111/j.1600-0536.1988.tb05507.x.

Abstract

1310 patients were routinely patch tested with a paratertiary-butylphenol-formaldehyde resin (PTBP-F-R), a resol resin based on phenol and formaldehyde (P-F-R-2), and a mixture of these 2 resins. Approximately 2.5 times more patients with contact allergy to phenol-formaldehyde resins were diagnosed when routinely patch tested with P-F-R-2 in addition to PTBP-F-R. Although patch testing with a mixture of both resins was not as good as patch testing with the 2 resins separately, it was better than testing only with PTBP-F-R, since 1.6 times more patients with contact allergy to phenol-formaldehyde resins were still diagnosed. P-F-R-2 is therefore recommended for routine patch testing, preferably as a separate patch test but otherwise as a mixture with PTBP-F-R.

MeSH terms

  • Dermatitis, Contact / etiology
  • Dermatitis, Occupational / chemically induced
  • Formaldehyde / immunology*
  • Humans
  • Patch Tests
  • Phenols / immunology*
  • Polymers / immunology*
  • Resins, Synthetic / immunology*

Substances

  • Phenols
  • Polymers
  • Resins, Synthetic
  • Formaldehyde
  • p-tert-butylphenolformaldehyde resin
  • phenol-formaldehyde resin