The North-South Divide: Substance Use Risk, Care Engagement, and Viral Suppression Among Hospitalized Human Immunodeficiency Virus-Infected Patients in 11 US Cities

Clin Infect Dis. 2019 Jan 1;68(1):146-149. doi: 10.1093/cid/ciy506.

Abstract

Regional variability in human immunodeficiency virus (HIV) care engagement remains underexplored. Multiple logistic models compared HIV outcomes for participants from 5 Southern (n = 557) and 6 non-Southern (n = 670) sites. Southern participants were less likely to experience viral suppression (adjusted odds ratio [aOR], 0.52; 95% confidence interval [CI], .37-.72) and had a higher likelihood of a CD4+ count <200 cells/µL (aOR, 1.53; 95% CI, 1.17-2.00). HIV intervention and social safety net programs should be expanded.

Clinical trials registration: NCT01612169.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • CD4 Lymphocyte Count
  • Cities / epidemiology
  • Facilities and Services Utilization / statistics & numerical data
  • Female
  • HIV Infections / complications*
  • HIV Infections / diagnosis
  • HIV Infections / drug therapy
  • HIV Infections / epidemiology*
  • Hospitalization
  • Humans
  • Male
  • Middle Aged
  • Substance-Related Disorders / complications*
  • Substance-Related Disorders / epidemiology*
  • United States / epidemiology
  • Viral Load

Associated data

  • ClinicalTrials.gov/NCT01612169