The epidemiology of Staphylococcus aureus infection in children is dynamic. We conducted a retrospective observational study on pediatric clinical cultures, performed between 2005 and 2017, that grew S aureus to determine temporal trends in antibiotic resistance. Although methicillin resistance declined, clindamycin and trimethoprim-sulfamethoxazole resistance increased significantly, especially among community-onset isolates.
Keywords: Staphylococcus aureus; antibiotic resistance; clindamycin; community-onset infection; pediatrics; trimethoprim-sulfamethoxazole.
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