Association of obstructive sleep apnoea with acute severity of chronic obstructive pulmonary disease exacerbation: a population-based study

Intern Med J. 2018 Sep;48(9):1150-1153. doi: 10.1111/imj.14016.

Abstract

Little is known about the association of obstructive sleep apnoea (OSA) with the severity of acute exacerbation of chronic obstructive pulmonary disease (AECOPD). This retrospective cohort study investigated the association of coexistent OSA with acute severity markers (i.e. invasive positive pressure ventilation (IPPV) use and hospital length of stay (LOS)) among adults hospitalised for AECOPD. Patients with coexistent OSA had a significantly higher risk of IPPV use and prolonged hospital LOS compared to those without OSA.

Keywords: COPD; hospital length of stay; mechanical ventilation; obstructive sleep apnoea; severity.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Disease Progression
  • Female
  • Humans
  • Length of Stay / statistics & numerical data
  • Male
  • Middle Aged
  • Pulmonary Disease, Chronic Obstructive / complications
  • Pulmonary Disease, Chronic Obstructive / epidemiology*
  • Retrospective Studies
  • Severity of Illness Index
  • Sleep Apnea, Obstructive / complications
  • Sleep Apnea, Obstructive / epidemiology*
  • United States / epidemiology