Delayed Return of Ejaculatory Function in Adolescent Males Treated With Retroperitoneal Lymph Node Dissection and Adjuvant Therapy for Paratesticular Rhabdomyosarcoma

Urology. 2019 Feb:124:254-256. doi: 10.1016/j.urology.2018.10.030. Epub 2018 Oct 23.

Abstract

Due to the rarity of the disease, adverse events related to ejaculatory function following the management of paratesticular rhabdomyosarcoma with multimodal therapy in adolescents are rarely discussed. Two patients, age 14 and 15 at time of diagnosis were treated with multimodal therapy with nerve-sparing retroperitoneal lymph node dissection, chemotherapy, and radiotherapy. Each developed ejaculatory dysfunction during the treatment period, which resolved 1 year after completion of all therapies. We sought to assess the role of each component of multimodal therapy on the observed side effect and the potential for delayed recovery of function after cessation of all therapies.

Publication types

  • Case Reports
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Chemoradiotherapy, Adjuvant
  • Ejaculation / physiology*
  • Humans
  • Lymph Node Excision* / methods
  • Male
  • Recovery of Function
  • Retroperitoneal Space
  • Rhabdomyosarcoma / surgery*
  • Testicular Neoplasms / surgery*
  • Time Factors