Adaptive Interventions Are Required for Efficient and Personalized Adolescent Depression Treatment

Abstract

Psychological treatments for adolescent depression demonstrate small to moderate effect sizes, with a substantial portion of youth showing insufficient response to treatment.^1,2 The management of an adolescent who has not responded to front-line treatments is a common clinical scenario in which clinicians, in the absence of compelling data to drive decision making, are left with having to take a trial-and-error approach in order to promote adequate treatment response.