Will converting naloxone to over-the-counter status increase pharmacy sales?

Health Serv Res. 2019 Aug;54(4):764-772. doi: 10.1111/1475-6773.13125. Epub 2019 Feb 20.

Abstract

Objective: To estimate the own-price elasticity of demand for naloxone, a prescription medication that can counter the effects of an opioid overdose, and predict the change in pharmacy sales following a conversion to over-the-counter status.

Data sources/study setting: The primary data source was a nationwide prescription claims dataset for 2010-2017. The data cover 80 percent of US retail pharmacies and account for roughly 90 percent of prescriptions filled. Additional covariates were obtained from various secondary data sources.

Study design: We estimated a longitudinal, simultaneous equation model of naloxone supply and demand. Our primary variables of interest were the quantity of naloxone sold, measured as total milligrams sold at pharmacies, and the out-of-pocket price paid per milligram, both measured per ZIP Code and quarter-year.

Data collection/extraction methods: Primary data came directly from payers and processors of prescription drug claims.

Principal findings: We found that, on average, a 1 percent increase in the out-of-pocket price paid for naloxone would result in a 0.27 percent decrease in pharmacy sales. We predict that the total quantity of naloxone sold in pharmacies would increase 15 percent to 179 percent following conversion to over-the-counter status.

Conclusions: Naloxone is own-price inelastic, and conversion to over-the-counter status is likely to lead to a substantial increase in total pharmacy sales.

Keywords: change in demand; naloxone; opioid overdose; over-the-counter conversion.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Commerce / statistics & numerical data*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Models, Economic
  • Naloxone / economics*
  • Narcotic Antagonists / economics*
  • Nonprescription Drugs / economics*
  • Pharmacies / economics*
  • Socioeconomic Factors

Substances

  • Narcotic Antagonists
  • Nonprescription Drugs
  • Naloxone