Cytoreduction and hyperthermic intraperitoneal chemotherapy in metastatic colorectal cancer

J Surg Oncol. 2019 Apr;119(5):613-615. doi: 10.1002/jso.25438. Epub 2019 Mar 10.

Abstract

As the management of metastatic colorectal cancer (CRC) has evolved over the past decades, optimal management of CRC with peritoneal metastases remains controversial, especially about cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. In this review, we highlight the current data on this challenging disease process, as well as comment on its limitations.

Keywords: colon cancer; cytoreductive surgery; hyperthermic intraperitoneal chemotherapy; intraperitoneal chemotherapy; peritoneal metastases; rectal cancer.

Publication types

  • Review

MeSH terms

  • Colorectal Neoplasms / pathology*
  • Colorectal Neoplasms / therapy
  • Cytoreduction Surgical Procedures / methods*
  • Humans
  • Hyperthermia, Induced / methods*
  • Peritoneal Neoplasms / secondary*
  • Peritoneal Neoplasms / therapy*