Predictors and Costs of 30-Day Readmissions After Index Hospitalizations for Alcohol-Related Disorders in U.S. Adults

Alcohol Clin Exp Res. 2019 May;43(5):857-868. doi: 10.1111/acer.14021. Epub 2019 Apr 10.

Abstract

Background: In 2015, the Hospital Readmissions Reduction Program mandated financial penalties to hospitals with greater rates of readmissions for certain conditions. Alcohol-related disorders (ARD) are the fourth leading cause of 30-day readmissions. Yet, there is a dearth of national-level research to identify high-risk patient populations and predictors of 30-day readmission. This study examined patient- and hospital-level predictors for index hospitalizations with principal diagnosis of ARD and predicted the cost of 30-day readmissions.

Methods: The 2014 Nationwide Readmissions Database was used to identify ARD-related index hospitalizations. Multivariable logistic regression was used to estimate patient- and hospital-level predictors for readmissions, and a 2-part model was used to predict the incremental cost conditional upon readmission.

Results: In 2014, 285,767 index hospitalizations for ARD were recorded, and 18.9% of ARD-associated hospitalizations resulted in at least one 30-day readmission. Patients who were males, aged 45 to 64 years, Medicaid enrollees, living in urban and low-income areas, or with 1 to 2 comorbidities had high risk of readmission. Index hospitalization costs were higher among readmitted patients ($8,840 vs. $8,036, p < 0.01). Predicted mean costs for readmissions on index stay with ARD were greater among those aged 45 to 64 years ($1,908, p < 0.001), Medicare enrollees ($2,133, p < 0.001), rural residents ($1,841, p < 0.01), living in high-income areas ($1,876, p < 0.001), with 4 or more comorbidities ($2,415, p < 0.001), or admitted in large metropolitan hospitals ($2,032, p < 0.001), with large number of beds ($1,964, p < 0.001), with government ownership ($2,109, p < 0.001), or with low volume of ARD cases ($2,155, p < 0.001).

Conclusions: One in 5 ARD-related index hospitalizations resulted in a 30-day readmission. Overall, costs of index hospitalizations for ARD were $2.3 billion, of which $512 million were spent on hospitalizations that resulted in at least 1 readmission. There is a need to develop patient-centric health programs to reduce readmission rates and costs among ARD patients.

Keywords: 30-Day Readmission; Alcohol-Related Disorders; Cost; Hospitalization; Patient Protection and Affordable Care Act.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Alcohol-Related Disorders / diagnosis
  • Alcohol-Related Disorders / economics*
  • Alcohol-Related Disorders / epidemiology*
  • Female
  • Forecasting
  • Health Care Costs / trends
  • Hospital Costs / trends*
  • Hospitalization / economics
  • Hospitalization / trends
  • Humans
  • Male
  • Middle Aged
  • Patient Readmission / economics*
  • Patient Readmission / trends*
  • United States / epidemiology
  • Young Adult