Five new drugs marketed in 2018 that are used for medical problems often experienced by the elderly have been selected for consideration in this review. The uses and most important properties of these agents are discussed, and a rating for each new drug is determined using the New Drug Comparison Rating system developed by the author (DAH). Advantages, disadvantages, and other important information regarding each new drug are identified and used as the basis for determining the rating. The drugs include two agents for type 2 diabetes mellitus, a drug for hyperkalemia, an antiviral agent for influenza, and a drug for the treatment of open-angle glaucoma and ocular hypertension.