Matching estimators for causal effects of multiple treatments

Stat Methods Med Res. 2020 Apr;29(4):1051-1066. doi: 10.1177/0962280219850858. Epub 2019 May 29.

Abstract

Matching estimators for average treatment effects are widely used in the binary treatment setting, in which missing potential outcomes are imputed as the average of observed outcomes of all matches for each unit. With more than two treatment groups, however, estimation using matching requires additional techniques. In this paper, we propose a nearest-neighbors matching estimator for use with multiple, nominal treatments, and use simulations to show that this method is precise and has coverage levels that are close to nominal. In addition, we implement the proposed inference methods to examine the effects of different medication regimens on long-term pain for patients experiencing motor vehicle collision.

Keywords: Causal inference; generalized propensity score; multiple testing; nominal exposure; observational data.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Causality
  • Cluster Analysis
  • Humans
  • Propensity Score
  • Research Design*