Psychiatric Comorbidity of Unipolar Mood, Anxiety, and Trauma Disorders Prior to HIV Testing and the Effect on Linkage to Care Among HIV-Infected Adults in South Africa

AIDS Behav. 2019 Dec;23(12):3444-3451. doi: 10.1007/s10461-019-02586-6.

Abstract

Psychiatric comorbidity, the presence of two or more psychiatric disorders, leads to worse HIV outcomes in the United States; this relationship has not been studied in sub-Saharan Africa. We conducted a preliminary study to describe the prevalence of psychiatric comorbidity (unipolar mood, anxiety, and trauma disorders) among 363 adults prior to HIV testing at Witkoppen Health and Welfare Centre, a primary care clinic in Johannesburg, South Africa. We also examined whether psychiatric comorbidity predicted subsequent linkage to HIV care 3 months later. Prevalence of psychiatric comorbidity prior to HIV testing was approximately 5.5%. In the final HIV-positive subsample (n = 76), psychiatric comorbidity of unipolar mood, anxiety, and trauma disorders did not predict linkage to care [adjusted relative risk = 1.01 (0.59, 1.71)] or number of follow-up appointments (adjusted relative risk = 0.86 (0.40, 1.82)]. A similar psychiatric profile emerged for HIV-positive and HIV-negative individuals before becoming aware of their HIV status. The psychiatric burden typically seen in HIV-positive individuals may manifest over time.

Keywords: HIV; Linkage to care; Psychiatric comorbidity; Psychiatric disorders; South Africa.

MeSH terms

  • Adult
  • Ambulatory Care Facilities
  • Anxiety Disorders / epidemiology*
  • Comorbidity
  • Depressive Disorder, Major / epidemiology*
  • Female
  • HIV Infections / epidemiology*
  • Humans
  • Male
  • Middle Aged
  • Prevalence
  • South Africa / epidemiology
  • Stress Disorders, Post-Traumatic / epidemiology*