In a pilot randomized trial in persons with opioid use disorder hospitalized with injection-related infections, an innovative care model combining outpatient parenteral antimicrobial therapy with buprenorphine treatment had similar clinical and drug use outcomes to usual care (inpatient intravenous antibiotic completion) and shortened hospital length of stay by 23.5 days.
Clinical trials registration: NCT03048643.
Keywords: antibiotics; buprenorphine; endocarditis; injection-drug use; opioid-related disorders.
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