Primary Aldosteronism Diagnosis and Management: A Clinical Approach

Abstract

Primary aldosteronism used to be considered a rare cause of secondary hypertension. However, accruing evidence indicates that primary aldosteronism is more common than previously recognized. The implications of this increased prevalence are important to public health because autonomous aldosterone production contributes to cardiovascular disease and can be treated in a targeted manner. This article focuses on clinical approaches for diagnosing primary aldosteronism more frequently and earlier in its course, as well as practical treatment objectives to reduce the risk for incident cardiovascular disease.

Keywords: Aldosterone; Cardiovascular disease; Cardiovascular morbidity; Hypertension; Primary aldosteronism.