Opioid-Limiting Regulation: Effect on Patients Undergoing Knee and Shoulder Arthroscopy

Arthroscopy. 2020 Mar;36(3):824-831. doi: 10.1016/j.arthro.2019.09.045. Epub 2019 Dec 19.

Abstract

Purpose: To determine the effect prescription-limiting legislation passed in Rhode Island has had on opioids prescribed following arthroscopic knee and shoulder surgery at various time points, up to 90 days postoperatively.

Methods: All patients undergoing the 3 most common arthroscopic procedures at our institution (anterior cruciate ligament reconstruction, partial meniscectomy, and rotator cuff repair) were included. Patients were selected from 2 6-month study periods (prepassage and postimplementation of the law). The state's Prescription Drug Monitoring Program database was queried for controlled substances filled in the perioperative period (from 30 days preoperatively to 90 days postoperatively). Multiple logistic regressions were used to identify predictors of chronic (>30 days) opioid use.

Results: The morphine milligram equivalents (MMEs) prescribed in the initial postoperative script decreased from 319.04 (∼43 5-mg oxycodone tablets) in the prepassage to 152.45 MMEs (∼20 5-mg oxycodone tablets) in the postimplementation group (P < .001). The total MMEs filled in the first 30 days decreased from 520.93 to 299.94 MMEs (∼70 to ∼40 5-mg oxycodone tablets) (P < .001). MMEs filled between 30 and 90 days fell by 22.5% for all patients in this study; however, this change was not statistically significant (P = .263). Preoperative opioid use (odds ratio, 10.85; P < .001) and preoperative benzodiazepine use (odds ratio, 2.13; P = .005) predicted chronic opioid use postoperatively.

Conclusions: State opioid-limiting legislation reduced cumulative MMEs following arthroscopic knee and shoulder surgery in the first 30 days. Further research assessing the impact of this legislation on postoperative pain control, patient satisfaction, and functional outcomes following surgery is warranted.

Level of evidence: Level III, case-control study.

MeSH terms

  • Analgesics, Opioid / adverse effects*
  • Arthroscopy
  • Case-Control Studies
  • Female
  • Humans
  • Knee Joint / surgery*
  • Legislation, Drug*
  • Male
  • Meniscectomy
  • Middle Aged
  • Odds Ratio
  • Oxycodone / adverse effects*
  • Pain, Postoperative / drug therapy*
  • Postoperative Period
  • Preoperative Period
  • Regression Analysis
  • Rhode Island
  • Risk Factors
  • Rotator Cuff / surgery
  • Shoulder / surgery*

Substances

  • Analgesics, Opioid
  • Oxycodone