Multiple Evanescent White Dot Syndrome: A Case Report and Experience with Corticosteroid Therapy

Iran J Allergy Asthma Immunol. 2020 May 17;19(S1):91-94. doi: 10.18502/ijaai.v19i(s1.r1).2865.

Abstract

Multiple evanescent white dot syndrome (MEWDS) is an inflammatory eye disease of the outer retina, retinal pigmented epithelium, choroid presenting with photopsia, loss of vision, and temporal scotoma. The patient was a 31-year-old female with a history of vision loss since 11 days ago (left eye). At presentation, best-corrected Snellen visual acuity was 20/140 in the Snellen chart. We decided to treat her with short time corticosteroid therapy (0.75 mg/kg/day prednisolone which was tapered in 3 weeks) for any possible rapid recovery of vision. The visual acuity of the involved eye was improved to 20/25 and 20/20, one week and three weeks after starting treatment respectively. Thus, it seems that short-term oral steroids might be an alternative method of management for patients with MEWDS.

Keywords: Inflammation; Prednisolone; White dot syndromes.

Publication types

  • Case Reports

MeSH terms

  • Administration, Oral
  • Adrenal Cortex Hormones / therapeutic use*
  • Adult
  • Anti-Inflammatory Agents / therapeutic use*
  • Child
  • Female
  • Humans
  • Optical Imaging
  • Prednisolone / therapeutic use*
  • Recovery of Function
  • Vision Disorders / diagnosis*
  • Vision Disorders / drug therapy
  • White Dot Syndromes / diagnosis*
  • White Dot Syndromes / drug therapy

Substances

  • Adrenal Cortex Hormones
  • Anti-Inflammatory Agents
  • Prednisolone