Evolving Impact of COVID-19 on Transplant Center Practices and Policies in the United States

Clin Transplant. 2020 Dec;34(12):e14086. doi: 10.1111/ctr.14086. Epub 2020 Sep 28.

Abstract

In our first survey of transplant centers in March 2020, >75% of kidney and liver programs were either suspended or operating under restrictions. To safely resume transplantation, we must understand the evolving impact of COVID-19 on transplant recipients and center-level practices. We therefore conducted a six-week follow-up survey May 7-15, 2020, and linked responses to the COVID-19 incidence map, with a response rate of 84%. Suspension of live donor transplantation decreased from 72% in March to 30% in May for kidneys and from 68% to 52% for livers. Restrictions/suspension of deceased donor transplantation decreased from 84% to 58% for kidneys and from 73% to 42% for livers. Resuming transplantation at normal capacity was envisioned by 83% of programs by August 2020. Exclusively using local recovery teams for deceased donor procurement was reported by 28%. Respondents reported caring for a total of 1166 COVID-19-positive transplant recipients; 25% were critically ill. Telemedicine challenges were reported by 81%. There was a lack of consensus regarding management of potential living donors or candidates with SARS-CoV-2. Our findings demonstrate persistent heterogeneity in center-level response to COVID-19 even as transplant activity resumes, making ongoing national data collection and real-time analysis critical to inform best practices.

Keywords: clinical decision-making; epidemiology; guidelines; infectious agents-viral.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, N.I.H., Intramural

MeSH terms

  • Adult
  • COVID-19 / diagnosis
  • COVID-19 / epidemiology
  • COVID-19 / etiology
  • COVID-19 / prevention & control*
  • COVID-19 Testing
  • Clinical Decision-Making
  • Follow-Up Studies
  • Health Care Surveys
  • Health Services Accessibility / organization & administration
  • Health Services Accessibility / trends*
  • Humans
  • Incidence
  • Infection Control / methods
  • Infection Control / trends
  • Organ Transplantation / methods
  • Organ Transplantation / trends*
  • Organizational Policy*
  • Postoperative Complications / epidemiology
  • Postoperative Complications / prevention & control
  • Postoperative Complications / virology
  • Practice Patterns, Physicians' / trends*
  • Telemedicine / trends*
  • Tissue and Organ Procurement / organization & administration
  • Tissue and Organ Procurement / trends*
  • United States / epidemiology