Epidemiologic and Microbiologic Characteristics of Hospitalized Patients Co-colonized With Multiple Species of Carbapenem-Resistant Enterobacteriaceae in the United States

Timileyin Adediran; Anthony D Harris; J Kristie Johnson; David P Calfee; Loren G Miller; M Hong Nguyen; Daniel J Morgan; Katherine E Goodman; Stephanie Hitchcock; Lisa Pineles; Lyndsay M O'Hara

doi:10.1093/ofid/ofaa386

Epidemiologic and Microbiologic Characteristics of Hospitalized Patients Co-colonized With Multiple Species of Carbapenem-Resistant Enterobacteriaceae in the United States

Open Forum Infect Dis. 2020 Aug 27;7(10):ofaa386. doi: 10.1093/ofid/ofaa386. eCollection 2020 Oct.

Affiliations

¹ Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.
² Department of Pathology, University of Maryland School of Medicine, Baltimore, Marlyand, USA.
³ Department of Medicine, Weill Cornell Medicine, New York, New York, USA.
⁴ Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, California, USA.
⁵ Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

Abstract

We describe the epidemiologic and microbiologic characteristics of patients co-colonized with different species of carbapenem-resistant Enterobacteriaceae (CRE) from 5 hospitals in 4 states. Twenty-eight of 313 patients (8.9%) were co-colonized with at least 2 different CRE species. Different species within the same patient showed identical mechanism resistance in 18/28 (64%) cases.

Keywords: CRE; co-colonization.

Epidemiologic and Microbiologic Characteristics of Hospitalized Patients Co-colonized With Multiple Species of Carbapenem-Resistant Enterobacteriaceae in the United States

Authors

Affiliations

Abstract

Grants and funding