Life underneath the VCA umbrella: Perspectives from the US Uterus Transplant Consortium

Am J Transplant. 2021 May;21(5):1699-1704. doi: 10.1111/ajt.16445. Epub 2021 Feb 19.

Abstract

The parallel emergence of uterus transplantation (UTx) and other transplantation innovations including face and hand transplantation led to the categorization of the uterus as a vascular composite allograft (VCA). With >60 transplants and >20 births worldwide, UTx is transitioning rapidly from a research endeavor to an effective treatment option for women with uterine factor infertility. While it originally made sense to group the innovations under one umbrella, it is time to revisit the designation of UTx as a VCA. We describe how UTx needs unique policy, procedural codes, insurance contracts, and educational initiatives. We contend that separating UTx from VCAs may become necessary in the future to avoid hindering the growth and regulation of this field.

Keywords: Organ Procurement and Transplantation Network (OPTN); United Network for Organ Sharing (UNOS); classification systems; editorial/personal viewpoint; vascularized composite and reconstructive transplantation.

MeSH terms

  • Female
  • Humans
  • Organ Transplantation*
  • Transplantation, Homologous
  • Transplants*
  • Treatment Outcome
  • Uterus / transplantation