TELEmedicine as an intervention for sepsis in emergency departments: a multicenter, comparative effectiveness study (TELEvISED Study)

Nicholas M Mohr; Karisa K Harland; Uche E Okoro; Brian M Fuller; Kalyn Campbell; Morgan B Swanson; Stephen Q Simpson; Edith A Parker; Luke J Mack; Amanda Bell; Katie DeJong; Brett Faine; Anne Zepeski; Keith Mueller; Elizabeth Chrischilles; Christopher R Carpenter; Michael P Jones; Marcia M Ward

doi:10.2217/cer-2020-0141

TELEmedicine as an intervention for sepsis in emergency departments: a multicenter, comparative effectiveness study (TELEvISED Study)

J Comp Eff Res. 2021 Feb;10(2):77-91. doi: 10.2217/cer-2020-0141. Epub 2021 Jan 20.

Authors

Nicholas M Mohr^{1

2

3}, Karisa K Harland¹, Uche E Okoro¹, Brian M Fuller^{4

5}, Kalyn Campbell^{1

6}, Morgan B Swanson^{1

3}, Stephen Q Simpson^{7

8}, Edith A Parker⁹, Luke J Mack^{10

11}, Amanda Bell¹⁰, Katie DeJong¹⁰, Brett Faine^{1

12

13}, Anne Zepeski^{1

13}, Keith Mueller¹⁴, Elizabeth Chrischilles³, Christopher R Carpenter⁵, Michael P Jones¹⁵, Marcia M Ward¹⁴

Affiliations

¹ Department of Emergency Medicine, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA.
² Division of Critical Care, Department of Anesthesia, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA.
³ Department of Epidemiology, University of Iowa College of Public Health, Iowa City, IA 52242, USA.
⁴ Division of Critical Care, Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO 63110, USA.
⁵ Department of Emergency Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
⁶ Department of Surgery, Hennepin County Medical Center, Minneapolis, MN 55415, USA.
⁷ Department of Pulmonary, Critical Care, & Sleep Medicine, University of Kansas, Kansas City, KS 66160, USA.
⁸ Biomedical Advanced Research & Development Authority, US Department of Health & Human Services, Washington, DC 20201, USA.
⁹ Department of Community & Behavioral Health, University of Iowa College of Public Health, Iowa City, IA 52242, USA.
¹⁰ Avera eCARE, Sioux Falls, SD 57104, USA.
¹¹ Department of Family Medicine, University of South Dakota School of Medicine, Sioux Falls, SD 57105, USA.
¹² Department of Pharmacy Practice & Science, College of Pharmacy, University of Iowa, Iowa City, IA 52242, USA.
¹³ Department of Pharmaceutical Care, University of Iowa Hospitals & Clinics, Department of Health Management & Policy, Iowa City, IA 52242, USA.
¹⁴ Department of Health Management and Policy, University of Iowa College of Public Health, Iowa City, IA 52242, USA.
¹⁵ Department of Biostatistics, University of Iowa College of Public Health, Iowa City, IA 52242, USA.

Abstract

Sepsis is a life-threatening infection that affects over 1.7 million Americans annually. Low-volume rural hospitals have worse sepsis outcomes, and emergency department (ED)-based telemedicine (tele-ED) has been one promising strategy for improving rural sepsis care. The objective of this study is to evaluate the impact of tele-ED consultation on sepsis care and outcomes in rural ED patients. The TELEvISED study is a multicenter (n = 25) retrospective propensity-matched comparative effectiveness study of tele-ED care for rural sepsis patients in a mature tele-ED network. Telemedicine-exposed patients will be matched with non telemedicine patients using a propensity score to predict tele-ED use. The primary outcome is 28-day hospital free days, and secondary outcomes include adherence with guidelines, mortality and organ failure. ClinicalTrials.gov: NCT04441944.

Keywords: emergency service; hospital; hospitals; rural; sepsis; telemedicine.

Publication types

Multicenter Study
Research Support, N.I.H., Extramural
Research Support, U.S. Gov't, P.H.S.

MeSH terms

Emergency Medical Services*
Emergency Service, Hospital
Humans
Retrospective Studies
Sepsis* / therapy
Telemedicine*

Associated data

ClinicalTrials.gov/NCT04441944

Abstract

Publication types

MeSH terms

Associated data

Grants and funding