The Postural Tachycardia Syndrome (PoTS) Bladder-Urodynamic Findings

Abstract

Objective: To evaluate the urodynamics (UDS) of patients with postural tachycardia syndrome (PoTS).

Methods: Patients with a confirmed diagnosis of PoTS referred by the department of neuro-cardiology to the neuro-urology were identified and their UDS were retrospectively reviewed.

Results: In total, 50 patients (47 = 94.0% female) with confirmed PoTS and available UDS were identified. Mean age of females and males was 32.4 and 28.2 years, P = .15. Intermittent self-catheterisation was being used by 15/47 (31.9%) females at assessment. Detrusor overactivity was observed in 6 females (12.8%) (all at end fill and associated with urgency). In total, 14 (29.8%) females had no sensation of filling. No patients had an "unsafe" bladder. In total, 15/47 (31.9%) of women were unable to void with UDS catheters. Straining was reported in 22/35 (68.8%) of females. The female bladder outflow obstruction index = P_DetQ_max - 2.2(Q_max) was over 5 in 10/28 (35.7%) and over 18 in 5 (17.9%). The bladder contractility index = P_DetQ_max + 5Q_max was under 100 in 18/28 (28.6%) women.

Conclusion: The UDS of patients with "PoTS bladder" often demonstrate a poorly sensate but stable and safe bladder with functional obstruction and impaired bladder contractility that may necessitate straining or intermittent self-catheterisation.