Cockroach-induced IL9, IL13, and IL31 expression and the development of allergic asthma in urban children

J Allergy Clin Immunol. 2021 May;147(5):1974-1977.e3. doi: 10.1016/j.jaci.2021.01.022. Epub 2021 Mar 9.

Abstract

Urban children who develop allergic sensitization and asthma have persistently elevated gene expression of the type 2 cytokines IL9, IL13, and IL31 in cockroach allergen stimulated PBMCs from age 2 through 7 years old.

Publication types

  • Letter
  • Research Support, N.I.H., Extramural

MeSH terms

  • Allergens / immunology*
  • Animals
  • Asthma / genetics
  • Asthma / immunology*
  • Child
  • Child, Preschool
  • Cockroaches / immunology*
  • Cytokines / genetics
  • Cytokines / immunology*
  • Female
  • Humans
  • Male
  • Transcriptome
  • Urban Population

Substances

  • Allergens
  • Cytokines