Nonclassical Monocytes (CD14dimCD16+) Are Associated With Carotid Intima-Media Thickness Progression for Men but Not Women: The Multi-Ethnic Study of Atherosclerosis-Brief Report

Arterioscler Thromb Vasc Biol. 2021 May 5;41(5):1810-1817. doi: 10.1161/ATVBAHA.120.315886. Epub 2021 Mar 25.

Abstract

[Figure: see text].

Keywords: atherosclerosis; carotid intima-media thickness; epidemiology; inflammation; monocytes.

Publication types

  • Comparative Study
  • Multicenter Study
  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Biomarkers / analysis
  • Carotid Artery Diseases / diagnostic imaging*
  • Carotid Artery Diseases / ethnology
  • Carotid Artery Diseases / immunology*
  • Carotid Intima-Media Thickness*
  • Case-Control Studies
  • Disease Progression
  • Female
  • Flow Cytometry
  • GPI-Linked Proteins / analysis
  • Humans
  • Immunophenotyping
  • Lipopolysaccharide Receptors / analysis*
  • Male
  • Middle Aged
  • Monocytes / immunology*
  • Phenotype
  • Predictive Value of Tests
  • Prospective Studies
  • Receptors, IgG / analysis*
  • Risk Assessment
  • Risk Factors
  • Sex Factors
  • Time Factors
  • United States / epidemiology

Substances

  • Biomarkers
  • CD14 protein, human
  • FCGR3B protein, human
  • GPI-Linked Proteins
  • Lipopolysaccharide Receptors
  • Receptors, IgG