Catch Me if You Can: Acute Events Hidden in Structured Chronic Disease Diagnosis Descriptions Show Detectable Recording Patterns in EHR

AMIA Annu Symp Proc. 2021 Jan 25:2020:373-382. eCollection 2020.

Abstract

Our previous research shows that structured cancer DX description data accuracy varied across electronic health record (EHR) segments (e.g. encounter DX, problem list, etc.). We provide initial evidence corroborating these findings in EHRs from patients with diabetes. We hypothesized that the odds of recording an "uncontrolled diabetes" DX increased after a hemoglobin A1c result above 9% and that this rate would vary across EHR segments. Our statistical models revealed that each DX indicating uncontrolled diabetes was 2.6% more likely to occur post-A1c>9% overall (adj-p=.0005) and 3.9% after controlling for EHR segment (adj-p<.0001). However, odds ratios varied across segments (1.021<OR<1.224, .0001<adj-p<.087). The number of providers (adj-p<.0001) and departments (adjp<.0001) also impacted the number of DX reporting uncontrolled diabetes. Segment heterogeneity must be accounted for when analyzing clinical data. Understanding this phenomenon will support accuracy-driven EHR data extraction to foster reliable secondary analyses of EHR data.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Chronic Disease*
  • Datasets as Topic
  • Diabetes Mellitus / diagnosis*
  • Electronic Health Records*
  • Glycated Hemoglobin / analysis
  • Humans
  • Machine Learning*
  • Medical Informatics / methods*
  • Models, Statistical
  • Odds Ratio

Substances

  • Glycated Hemoglobin A