Association between Chlamydia and routine place for healthcare in the United States: NHANES 1999-2016

PLoS One. 2021 May 10;16(5):e0251113. doi: 10.1371/journal.pone.0251113. eCollection 2021.

Abstract

Background: The United States is experiencing a surge in Chlamydia trachomatis (CT) infections representing a critical need to improve sexually transmitted infection (STI) screening and treatment programs. To understand where patients with STIs seek healthcare, we evaluated the relationship between CT infections and the place where individuals report usually receiving healthcare.

Methods: Our study used a nationally representative sample from the National Health and Nutrition Examination Survey (NHANES) from 1999 to 2016. The study population is adult patients, aged 18 to 39 years in whom a urine CT screen was obtained. Logistic regression models were used to determine if location of usual healthcare was predictive of a positive urine CT screen result. Models were adjusted for known confounders including age, gender, race/ethnicity, education, and insurance status.

Results: In this nationally representative sample (n = 19,275; weighted n = 85.8 million), 1.9% of individuals had a positive urine CT result. Participants reported usually going to the doctor's office (70.3%), "no place" (24.8%), Emergency Department (ED) (3.3%), or "other" place (1.7%) for healthcare. In adjusted models, the predicted probability of having a positive urine CT result is higher (4.9% vs 3.2%, p = 0.022; OR = 1.58) among those that reported the ED as their usual place for healthcare compared to those that reported going to a doctor's office or clinic.

Conclusions: Individuals having a positive urine CT screen are associated with using the ED as a usual source for healthcare. Understanding this association has the potential to improve STI clinical and policy interventions as the ED may be a critical site in combatting the record high rates of STIs.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Chlamydia Infections / epidemiology*
  • Chlamydia Infections / microbiology
  • Chlamydia Infections / pathology
  • Chlamydia Infections / therapy*
  • Chlamydia trachomatis / isolation & purification*
  • Databases, Factual
  • Delivery of Health Care / methods
  • Emergency Service, Hospital
  • Female
  • Humans
  • Male
  • Nutrition Surveys / methods
  • Prevalence
  • Retrospective Studies
  • Sexually Transmitted Diseases / epidemiology*
  • Sexually Transmitted Diseases / microbiology
  • Sexually Transmitted Diseases / pathology
  • Sexually Transmitted Diseases / therapy*
  • United States / epidemiology
  • Young Adult

Grants and funding

CDJ acknowledges funding from the National Clinician Scholars Program and the United States Department of Veterans Affairs supporting his work on this project. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.