Lack of Association of Household Income and Acute Gastroenteritis Disease Severity in Young Children: A Cohort Study

Acad Pediatr. 2022 May-Jun;22(4):581-591. doi: 10.1016/j.acap.2021.07.009. Epub 2021 Jul 16.

Abstract

Objective: To determine if low household income is associated with disease severity following emergency department (ED) discharge in children with acute gastroenteritis (AGE).

Methods: We conducted a secondary analysis employing data collected in 10 US-based tertiary-care, pediatric EDs between 2014 and 2017. Participants were aged 3 to 48 months and presented for care due to AGE. Income status was defined based on 1) home ZIP Code median annual home income and 2) percentage of home ZIP Code households below the poverty threshold. The primary outcome was moderate-to-severe AGE, defined by a post-ED visit Modified Vesikari Scale (MVS) score ≥9. Secondary outcomes included in-person revisits, revisits with intravenous rehydration, hospitalization, and etiologic pathogens.

Results: About 943 (97%) participants with a median age of 17 months (interquartile range 10, 28) completed follow-up. Post-ED visit MVS scores were lower for the lowest household income group (adjusted: -0.60; 95% confidence interval [CI]: -1.13, -0.07). Odds of experiencing an MVS score ≥9 did not differ between groups (adjusted odds ratio: 0.91; 95% CI: 0.54, 1.52). No difference in the post-ED visit MVS score or the proportion of participants with scores ≥9 was observed using the national poverty threshold definition. For both income definitions, there were no differences in terms of revisits following discharge, hospitalizations, and intravenous rehydration. Bacterial enteropathogens were more commonly identified in the lowest socioeconomic group using both definitions.

Conclusions: Lower household income was not associated with increased disease severity or resource use. Economic disparities do not appear to result in differences in the disease course of children with AGE seeking ED care.

Keywords: child; emergency service; gastroenteritis; hospital; income; poverty.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Child
  • Child, Preschool
  • Cohort Studies
  • Emergency Service, Hospital
  • Fluid Therapy
  • Gastroenteritis* / complications
  • Gastroenteritis* / epidemiology
  • Gastroenteritis* / therapy
  • Humans
  • Infant
  • Severity of Illness Index