Current Considerations for Clinical Management and Care of People with HIV: Findings from the 11th Annual International HIV and Aging Workshop

Asante R Kamkwalala; Ankita Garg; Upal Roy; Avery Matthews; Jose Castillo-Mancilla; Jordan E Lake; Giada Sebastiani; Michael Yin; Todd T Brown; Angela R Kamer; Douglas A Jabs; Ronald J Ellis; Marta Boffito; Meredith Greene; Sarah Schmalzle; Eugenia Siegler; Kristine M Erlandson; David J Moore

doi:10.1089/AID.2021.0059

Current Considerations for Clinical Management and Care of People with HIV: Findings from the 11th Annual International HIV and Aging Workshop

AIDS Res Hum Retroviruses. 2021 Nov;37(11):807-820. doi: 10.1089/AID.2021.0059. Epub 2021 Sep 20.

Authors

Asante R Kamkwalala¹, Ankita Garg², Upal Roy³, Avery Matthews⁴, Jose Castillo-Mancilla⁵, Jordan E Lake⁶, Giada Sebastiani⁷, Michael Yin⁸, Todd T Brown⁹, Angela R Kamer¹⁰, Douglas A Jabs^{11

12}, Ronald J Ellis^{13

14}, Marta Boffito¹⁵, Meredith Greene¹⁶, Sarah Schmalzle¹⁷, Eugenia Siegler¹⁸, Kristine M Erlandson⁵, David J Moore¹⁴

Affiliations

¹ Department of Neurology, Johns Hopkins University, Baltimore, Maryland, USA.
² Department of Infectious Diseases, University of Georgia, Athens, Georgia, USA.
³ Department of Health and Biomedical Sciences, The University of Texas Rio Grande Valley, Brownsville, Texas, USA.
⁴ Department of Psychiatry, South Texas Veteran Health Care System, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
⁵ Department of Medicine, Division of Infectious Disease, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
⁶ Department of Internal Medicine, University of Texas Health Science Center at Houston, Houston, Texas, USA.
⁷ Department of Medicine, McGill University Health Centre, Montreal, Canada.
⁸ Department of Infectious Disease, Columbia University, New York, New York, USA.
⁹ Department of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.
¹⁰ Department of Periodontology and Implant Dentistry, New York University College of Dentistry, New York, New York, USA.
¹¹ Department of Epidemiology, The Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USA.
¹² Department of Ophthalmology, The Wilmer Eye Institute, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
¹³ Department of Neurosciences, University of California San Diego, La Jolla, California, USA.
¹⁴ Department of Psychiatry, University of California San Diego, La Jolla, California, USA.
¹⁵ Department of HIV Services, Chelsea and Westminster Hospital, London, United Kingdom.
¹⁶ Division of Geriatrics, Department of Medicine, University of California San Francisco, San Francisco, California, USA.
¹⁷ Department of Infectious Disease, University of Maryland, Baltimore, Maryland, USA.
¹⁸ Division of Geriatrics and Palliative Medicine, Weill Cornell Medicine, New York, New York, USA.

Abstract

The number of people with HIV (PWH) aged 50 years or older continues to steadily increase. The convergence of age- and HIV-related complications in these individuals presents a challenge for both patients and clinicians alike. New findings continue to emerge, as numerous researchers evaluate the combined impact of these two factors on quality of life, physiological systems, and mental health in PWH. Since its first occurrence in 2009, the International Workshop on HIV and Aging has served as a multidisciplinary meeting to share basic biomedical data, clinical trial results, treatment strategies, and epidemiological recommendations, toward better understanding and outcomes among like-minded scientific professionals. In this article, we share a selection of key findings presented in plenary talks at the 11th Annual International Workshop on HIV and Aging, held virtually from September 30, 2020 to October 2, 2020. We will also address the future directions of HIV and aging research, to further assess how the aging process intersects with chronic HIV.

Keywords: HIV; aging; antiretroviral therapy; clinical outcomes; neuroscience.

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Aging
HIV Infections* / drug therapy
HIV Infections* / epidemiology
Humans
Quality of Life*

Abstract

Publication types

MeSH terms

Grants and funding