An evidence map of treatments for infantile epilepsy

Epilepsy Res. 2021 Dec:178:106781. doi: 10.1016/j.eplepsyres.2021.106781. Epub 2021 Oct 28.

Abstract

Epilepsy prevalence is high among infants, but treatment guidelines are not clear. We conducted a scoping review of interventions to manage epilepsy in infants, and identified 37 studies. Most studies reported that interventions were effective (22 studies; 76 %), but randomized controlled trials were uncommon (7 studies; 19 %) and sample sizes were small (range: 2 to 284 participants; mean: 69.4; 95 % confidence interval: 49.5, 89.2). Additional high quality research and systematic reviews on interventions for infantile epilepsy are needed to establish better treatment guidelines for the disease.

Keywords: Epilepsy; Evidence map; Infants; Scoping review.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Epilepsy* / epidemiology
  • Epilepsy* / therapy
  • Humans
  • Infant