Changes in Antihypertensive Medication Following Bariatric Surgery

Obes Surg. 2022 Apr;32(4):1312-1324. doi: 10.1007/s11695-022-05893-5. Epub 2022 Jan 26.

Abstract

Obesity is a leading cause of hypertension (i.e., high blood pressure [BP]). While hypertension can be managed with antihypertensive medication, substantial weight loss can also lower BP, reducing the need for antihypertensive medication. Articles in this review (n = 60) presented data on antihypertensive medication use among adults pre- and postoperatively. Roux-en-Y gastric bypass was the most studied surgical approach followed by Laparoscopic Sleeve Gastrectomy. Antihypertensive medication was discontinued in a large proportion of patients after surgery, and the mean number of antihypertensive medications decreased by approximately one. In almost a third of the studies, over 75% of participants experienced hypertension remission. All articles aside from two reported a decrease in systolic BP, with about 40% reporting a decrease of ≥ 10 mm Hg.

Publication types

  • Review
  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Antihypertensive Agents / therapeutic use
  • Bariatric Surgery*
  • Gastrectomy
  • Gastric Bypass*
  • Humans
  • Hypertension* / drug therapy
  • Hypertension* / surgery
  • Laparoscopy*
  • Obesity, Morbid* / surgery
  • Treatment Outcome

Substances

  • Antihypertensive Agents