Biological functions of DEAD/DEAH-box RNA helicases in health and disease

Ourania Andrisani; Qian Liu; Patricia Kehn; Wolfgang W Leitner; Kyung Moon; Nancy Vazquez-Maldonado; Ian Fingerman; Michael Gale Jr

doi:10.1038/s41590-022-01149-7

Biological functions of DEAD/DEAH-box RNA helicases in health and disease

Nat Immunol. 2022 Mar;23(3):354-357. doi: 10.1038/s41590-022-01149-7.

Authors

Ourania Andrisani¹, Qian Liu², Patricia Kehn², Wolfgang W Leitner², Kyung Moon³, Nancy Vazquez-Maldonado², Ian Fingerman⁴, Michael Gale Jr⁵

Affiliations

¹ Department of Basic Medical Sciences and Purdue Center for Cancer Research, Purdue University, West Lafayette, IN, USA.
² Division of Allergy, Immunology, and Transplantation, National Institute of Allergy and Infectious Diseases, Rockville, MD, USA.
³ Division of Blood Diseases and Resources, National Heart, Lung, and Blood Institute, Bethesda, MD, USA.
⁴ Division of Cancer Biology, National Cancer Institute, Rockville, MD, USA.
⁵ Center for Innate Immunity and Immune Disease, Department of Immunology, University of Washington, Seattle, WA, USA. mgale@uw.edu.

Abstract

On 15–16 November 2021 the National Institute of Allergy and Infectious Diseases (NIAID), the National Cancer Institute (NCI), and the National Heart, Lung, and Blood Institute (NHLBI) hosted a virtual workshop on DEAD/DEAH-box RNA helicases in health and disease. The goal of the workshop was to review current advances, and to identify knowledge gaps and future research directions for improving our understanding of the function of RNA helicases, and leveraging these molecules as molecular targets with translational potential.

Publication types

Research Support, N.I.H., Extramural

MeSH terms

DEAD-box RNA Helicases* / genetics
RNA
RNA Helicases* / genetics

Substances

RNA
DEAD-box RNA Helicases
RNA Helicases

Abstract

Publication types

MeSH terms

Substances

Grants and funding