Disparities in surgical outcomes of neonates with congenital heart disease across regions, centers, and populations

Semin Perinatol. 2022 Jun;46(4):151581. doi: 10.1016/j.semperi.2022.151581. Epub 2022 Mar 13.

Abstract

Objective: To summarize existing literature on neonatal disparities in congenital heart disease surgical outcomes and identify potential policies to address these disparities.

Finding: Disparities in outcomes for neonatal congenital heart surgery were largely published under four domains: race/ethnicity, insurance type, neighborhood/socioeconomic status, and cardiac center characteristics. While existing research identifies associations between these domains and mortality, more nuanced analyses are emerging to understand the mediators between these domains and other non-mortality outcomes, as well as potential interventions and policies to reduce disparities. A broader look into social determinants of health (SDOH), prenatal diagnosis, proximity of birth to a cardiac surgical center, and post-surgical outpatient and neurodevelopmental follow-up may accelerate interventions to mitigate disparities in outcomes.

Conclusion: Understanding the mechanisms of how SDOH relate to neonatal surgical outcomes is paramount, as disparities research in neonatal congenital heart surgery continues to shift from identification and description, to intervention and policy.

Keywords: Congenital Heart Disease; Social Determinants of Health; congenital heart surgery; health disparities; neonatal.

MeSH terms

  • Cardiac Surgical Procedures*
  • Ethnicity
  • Health Status Disparities
  • Heart Defects, Congenital* / surgery
  • Humans
  • Infant, Newborn
  • Social Determinants of Health
  • Treatment Outcome