piRNA 3' uridylation facilitates the assembly of MIWI/piRNA complex for efficient target regulation in mouse male germ cells

Mao-Zhou Zhao; Di-Hang Lin; Heng Zuo; Huan Wei; Xin Wang; Lan-Tao Gou; Mo-Fang Liu

doi:10.1038/s41422-022-00659-1

piRNA 3' uridylation facilitates the assembly of MIWI/piRNA complex for efficient target regulation in mouse male germ cells

Cell Res. 2022 Nov;32(11):1030-1033. doi: 10.1038/s41422-022-00659-1. Epub 2022 Apr 15.

Authors

Mao-Zhou Zhao^#¹, Di-Hang Lin^#¹, Heng Zuo^#¹, Huan Wei², Xin Wang^{3

4}, Lan-Tao Gou⁵, Mo-Fang Liu^{6

7

8}

Affiliations

¹ State Key Laboratory of Molecular Biology, State Key Laboratory of Cell Biology, Shanghai Key Laboratory of Molecular Andrology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences; University of Chinese Academy of Sciences, Shanghai, China.
² School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, Zhejiang, China.
³ State Key Laboratory of Molecular Biology, State Key Laboratory of Cell Biology, Shanghai Key Laboratory of Molecular Andrology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences; University of Chinese Academy of Sciences, Shanghai, China. wx@ucas.ac.cn.
⁴ School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, Zhejiang, China. wx@ucas.ac.cn.
⁵ State Key Laboratory of Molecular Biology, State Key Laboratory of Cell Biology, Shanghai Key Laboratory of Molecular Andrology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences; University of Chinese Academy of Sciences, Shanghai, China. goulantao@sibcb.ac.cn.
⁶ State Key Laboratory of Molecular Biology, State Key Laboratory of Cell Biology, Shanghai Key Laboratory of Molecular Andrology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences; University of Chinese Academy of Sciences, Shanghai, China. mfliu@sibcb.ac.cn.
⁷ School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, Zhejiang, China. mfliu@sibcb.ac.cn.
⁸ School of Life Science and Technology, Shanghai Tech University, Shanghai, China. mfliu@sibcb.ac.cn.

^# Contributed equally.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Argonaute Proteins* / genetics
Argonaute Proteins* / metabolism
Germ Cells / metabolism
Male
Mice
RNA, Small Interfering* / genetics
RNA, Small Interfering* / metabolism
Spermatogenesis* / genetics
Testis / metabolism

Substances

Argonaute Proteins
RNA, Small Interfering