The timing of Start is determined primarily by increased synthesis of the Cln3 activator rather than dilution of the Whi5 inhibitor

Affiliations

• ¹ Molecular Systems Biology, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, 9747 AG Groningen, Netherlands.
• ² Biological Sciences, Rensselaer Polytechnic Institute, Troy, NY 12180.
• ³ Institute for Research in Immunology and Cancer, University of Montréal, Montréal, H3T 1J4 QC, Canada.
• ⁴ Proteomics Core Facility, Biozentrum, University of Basel, 4056 Basel, Switzerland.
• ⁵ Institute of Biomedicine, University of Eastern Finland, FI-70210 Kuopio, Finland.