A lead selective dimeric quinoline based fluorescent chemosensor and its applications in milk and honey samples, smartphone and bio-imaging

G Prabakaran; R Vickram; K Velmurugan; C Immanuel David; S Prince Makarios Paul; Raju Suresh Kumar; Abdulrahman I Almansour; Karthikeyan Perumal; A Abiram; J Prabhu; R Nandhakumar

doi:10.1016/j.foodchem.2022.133617

A lead selective dimeric quinoline based fluorescent chemosensor and its applications in milk and honey samples, smartphone and bio-imaging

Food Chem. 2022 Nov 30:395:133617. doi: 10.1016/j.foodchem.2022.133617. Epub 2022 Jul 3.

Authors

Affiliations

¹ Fluorensic Materials Lab, Department of Applied Chemistry, Karunya Institute of Technology and Sciences (Deemed-to-be University), Karunya Nagar, Coimbatore 641 114, India.
² College of Material Science and Technology, Nanjing University of Aeronautics and Astronautics, Nanjing 211100, China.
³ Department of Applied Physics, Karunya Institute of Technology and Sciences (Deemed-to-be University), Karunya Nagar, Coimbatore 641 114, India.
⁴ Department of Chemistry, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.
⁵ Department of Chemistry and Biochemistry, The Ohio State University, 151 W. Woodruf Ave, Columbus, OH 43210, USA.
⁶ Department of Applied Physics, Karunya Institute of Technology and Sciences (Deemed-to-be University), Karunya Nagar, Coimbatore 641 114, India. Electronic address: abiram@karunya.edu.
⁷ Fluorensic Materials Lab, Department of Applied Chemistry, Karunya Institute of Technology and Sciences (Deemed-to-be University), Karunya Nagar, Coimbatore 641 114, India. Electronic address: nandhakumar@karunya.edu.

PMID: 35802967
DOI: 10.1016/j.foodchem.2022.133617

Abstract

Dimeric quinoline-based Schiff base was developed (DQS) for the specific detection of Pb²⁺ ion via fluorimetry. DQS coordinates with Pb²⁺, a variation in fluorescence intensity with enhanced radical blue shift was observed due to the restriction of CN rotation, CN isomerization, and photoinduced electron transfer (PET) mechanisms. In addition, the intramolecular charge transfer (ICT) from electron-donating morpholine to phenylene diamine acceptor linked quinoline bridge is responsible for the blue-shifted fluorescence enhancement in the DQS-Pb²⁺ complex. The binding stoichiometry of DQS: Pb²⁺ (1:2) was confirmed by host-guest titration and mass spectrometry. The limit of detection (LOD) of the DQS was found to be 1.3 × 10^-7 M for Pb²⁺ ion. The DQS sensing ability of Pb²⁺ was further applied into milk and honey samples, smartphone, bio-imaging and to construct of an INHIBIT molecular logic gate.

Keywords: Chemosensor; Fluorescence; Honey detection; ICT; Pb(2+); Smartphone.

MeSH terms

Fluorescent Dyes / chemistry
Honey*
Lead
Quinolines* / chemistry
Smartphone
Spectrometry, Fluorescence / methods

Substances

Fluorescent Dyes
Quinolines
Lead