Acute Enophthalmos After Lumbar Puncture in a Patient with Type 1 Neurofibromatosis Related Sphenoid Wing Dysplasia

Deanna Ingrassia Miano; Gregory Byrd; Rani Kattoula; Aye Thet; Ryan Adkins; Ryan Cosgrove; Samantha S Johnson

doi:10.1080/01658107.2022.2034891

Acute Enophthalmos After Lumbar Puncture in a Patient with Type 1 Neurofibromatosis Related Sphenoid Wing Dysplasia

Neuroophthalmology. 2022 Feb 15;46(4):270-274. doi: 10.1080/01658107.2022.2034891. eCollection 2022.

Authors

Deanna Ingrassia Miano¹, Gregory Byrd², Rani Kattoula², Aye Thet², Ryan Adkins³, Ryan Cosgrove¹, Samantha S Johnson¹

Affiliations

¹ Department of Ophthalmology, Ascension Macomb-Oakland Hospital, Warren, Michigan, USA.
² Department of Internal Medicine, Ascension Macomb-Oakland Hospital, Warren, Michigan, USA.
³ Department of Emergency Medicine, Ascension Macomb-Oakland Hospital, Warren, Michigan, USA.

Abstract

A 19-year-old woman with type 1 neurofibromatosis related sphenoid wing dysplasia underwent a lumbar puncture (LP) after an unexplained syncopal event. The cerebrospinal fluid work-up was unremarkable. However, 30-hours post LP, she developed marked enophthalmos ipsilateral to the calvarial dysplasia. The enophthalmos gradually resolved within 72 hours. We surmise that the patient's enophthalmos was due to an LP induced decrease of intracranial pressure in conjunction with the orbital bone anomaly.

Keywords: Enophthalmos; intracranial hypotension; neurofibromatosis type 1; sphenoid wing dysplasia.

Publication types

Case Reports

Grants and funding

The authors reported there is no funding associated with the work featured in this article.