Prevention of submicron aerosolized particle dispersion: evaluation of an aerosol box using a pediatric simulation model

Exp Lung Res. 2022 Nov-Dec;48(9-10):266-274. doi: 10.1080/01902148.2022.2135795. Epub 2022 Oct 21.

Abstract

Background and Aim: The SplashGuard CG (SG) is a barrier enclosure developed to protect healthcare workers from SARS-CoV-2 transmission during aerosol-generating procedures. Our objective was to evaluate the protection provided by the SG against aerosolized particles (AP), using a pediatric simulation model of spontaneous ventilation (SV) and noninvasive ventilation (NIV). Methods: An aerosol generator was connected to the airways of a pediatric high-fidelity manikin with a breathing simulator. AP concentrations were measured both in SV and NIV in the following conditions: with and without SG, inside and outside the SG, with and without suction applied to the device. Results: In the SV simulated setting, AP peaks were lower with SG: 0.1 × 105 particles/L compared to without: 1.6 × 105, only when the ports were closed and suction applied. In the NIV simulated setting, AP peaks outside the SG were lower than without SG (20.5 × 105 particles/L), whatever the situation, without suction (14.4 × 105particles/L), with suction and ports open or closed: 10.3 and 0.7 × 105 particles/L. In SV and NIV simulated settings, the AP peaks measured within the SG were much higher than the AP peaks measured without SG, even when suction was applied to the device. Conclusions: The SG seems to decrease peak AP exposure in the 2 ventilation contexts, but only with closed port and suction in SV. However, high concentrations of AP remain inside even with suction and SG should be used cautiously.

Keywords: Aerosol; COVID-19; aerosol box; children; simulation.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aerosolized Particles and Droplets*
  • COVID-19* / prevention & control
  • Child
  • Humans
  • Respiratory Aerosols and Droplets
  • SARS-CoV-2
  • Suction

Substances

  • Aerosolized Particles and Droplets