Recurrent Neisseria cinerea bacteremia secondary to cardiovascular implantable electronic device infection

Zachary S Bernstein; James J Vaillant; Hector I Michelena; Sorin V Pislaru; Daniel C DeSimone

doi:10.1016/j.idcr.2023.e01745

Recurrent Neisseria cinerea bacteremia secondary to cardiovascular implantable electronic device infection

IDCases. 2023 Mar 9:32:e01745. doi: 10.1016/j.idcr.2023.e01745. eCollection 2023.

Authors

Zachary S Bernstein¹, James J Vaillant², Hector I Michelena³, Sorin V Pislaru³, Daniel C DeSimone²

Affiliations

¹ Center for Multiple Myeloma, Massachusetts General Hospital Cancer Center, Boston, MA 02114, USA.
² Division of Public Health, Infectious Diseases, and Occupational Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.
³ Divisions of Structural Heart Disease and Cardiovascular Ultrasound, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.

Abstract

We present the first case of cardiac implantable electronic device (CIED) infection due to Neisseria cinerea in a 64-year-old woman from Panama. She had a history of splenectomy, aortic valve stenosis requiring transcatheter aortic valve replacement (TAVR), and permanent pacemaker placement. She presented with relapsing N. cinerea bacteremia over a 3-month period. Transesophageal echocardiography revealed a lead vegetation in the superior vena cava. She was successfully treated with pacemaker removal and 2 weeks of IV antibiotic therapy. N. cinerea is an aerobic gram-negative commensal diplococcus typically found in the human nasopharynx. Infection in humans is rare with few case reports in the literature.

Keywords: Asplenia; Cardiovascular implantable electronic device infection; Neisseria cinerea.

Publication types

Case Reports