Perspectives on deprescribing in palliative care

Expert Rev Clin Pharmacol. 2023 May;16(5):411-421. doi: 10.1080/17512433.2023.2197592. Epub 2023 Apr 19.

Abstract

Introduction: Pharmacotherapy plays a critical role in the delivery of high-quality palliative care, but the intersection of palliative care and deprescribing has received little attention.

Areas covered: We conducted a scoping review of English language articles using PubMed to identify relevant publications between 1 January 2000 to 31 July 2022 using search terms of deprescribing, palliative care, end of life, and hospice. We summarize current definitions and developments in palliative care and deprescribing from both clinical and research perspectives. We highlight key challenges and outline proposed solutions and needed research.

Expert opinion: The future of deprescribing in palliative care requires the development and adoption of individualized approaches to medication management, including a reconsidered approach to communication about deprescribing. Evidence from high-quality clinical outcomes studies is lacking, and the field needs new approaches to coordination of care delivery. This review article will be of interest to both clinical and research-based pharmacists, physicians, and nurses interested in improving care for patients with serious illness.

Keywords: Deprescribing; caregivers; end of life; goal concordant prescribing; life-limiting illness; palliative care; serious illness.

Publication types

  • Review

MeSH terms

  • Communication
  • Deprescriptions*
  • Humans
  • Palliative Care
  • Pharmacists
  • Physicians*