Prophylactic Uterine Artery Embolization in Placenta Accreta Spectrum-An Active Intervention to Reduce Morbidity and Promote Uterine Preservation

J Vasc Interv Radiol. 2023 Nov;34(11):1922-1928. doi: 10.1016/j.jvir.2023.07.020. Epub 2023 Jul 28.

Abstract

Purpose: To evaluate the feasibility and safety of early and proactive involvement of interventional radiology (IR) in the management of placenta accreta spectrum (PAS) by performing the cesarean operation and prophylactic uterine artery embolization in the IR angiography suite as a combined procedure.

Materials and methods: This study evaluated the effectiveness and safety of prophylactic uterine artery embolization prior to placental separation in cases of antenatally proven or suspected abnormal placentation. Over a 5-year period, 16 consecutive patients with PAS underwent combined IR and obstetric intervention. In all cases, cesarean delivery was performed in the IR angiography suite. Vascular access was obtained prior to surgery with balloon placement into both internal iliac arteries. These balloons were inflated after delivery, followed by uterine artery embolization (14 of 16) if there was evidence of active postpartum bleeding or inability to deliver the placenta.

Results: There was no fetal or maternal mortality and no significant IR or surgical adverse events. Mean blood loss was 1900 mL. Seven patients (44%) underwent hysterectomy.

Conclusions: In patients with PAS, cesarean section in the angiography suite preceded by prophylactic balloon placement and followed by uterine artery embolization was feasible, safe, and effective in preventing massive blood loss, with a 56% uterine sparing rate.

MeSH terms

  • Balloon Occlusion* / adverse effects
  • Balloon Occlusion* / methods
  • Blood Loss, Surgical / prevention & control
  • Cesarean Section / adverse effects
  • Female
  • Humans
  • Hysterectomy
  • Iliac Artery
  • Morbidity
  • Placenta
  • Placenta Accreta* / surgery
  • Placenta Accreta* / therapy
  • Postpartum Hemorrhage* / etiology
  • Postpartum Hemorrhage* / prevention & control
  • Pregnancy
  • Retrospective Studies
  • Uterine Artery Embolization* / adverse effects