Ischemia Duration and Lower Limb Salvage

Alexis L Lauria; Caitlin W Hicks

doi:10.1016/j.yasu.2023.05.003

Ischemia Duration and Lower Limb Salvage

Adv Surg. 2023 Sep;57(1):59-71. doi: 10.1016/j.yasu.2023.05.003. Epub 2023 Jun 25.

Authors

Alexis L Lauria¹, Caitlin W Hicks²

Affiliations

¹ Department of Surgery, Walter Reed National Military Medical Center, 8901 Rockville Pike, Bethesda, MD 20889, USA.
² Division of Vascular Surgery and Endovascular Therapy, Johns Hopkins University School of Medicine, Johns Hopkins Hospital, 600 North Wolfe Street - Halsted 668, Baltimore, MD 21287, USA. Electronic address: chicks11@jhmi.edu.

PMID: 37536862
PMCID: PMC10773526 (available on 2024-09-01)
DOI: 10.1016/j.yasu.2023.05.003

Abstract

Management of acute limb ischemia is complex and time sensitive, and delays in diagnosis and treatment may lead to irreversible tissue damage. Current data challenge the commonly accepted 6-hour ischemic threshold for acute limb ischemia, although variations in practice remain. Patients with chronic peripheral artery disease may tolerate longer ischemia time due to presence of collateral circulation. Here the authors discuss the presentation, workup, management, and postoperative care of patients with acute limb ischemia, with a focus on how management is altered depending on the duration and degree of ischemia.

Keywords: Acute limb ischemia; Ischemia duration; Limb revascularization; Limb salvage.

Publication types

Review
Research Support, N.I.H., Extramural

MeSH terms

Humans
Ischemia / diagnosis
Ischemia / etiology
Ischemia / surgery
Limb Salvage*
Lower Extremity / blood supply
Peripheral Arterial Disease* / diagnosis
Peripheral Arterial Disease* / surgery
Retrospective Studies
Risk Factors
Treatment Outcome

Abstract

Publication types

MeSH terms

Grants and funding