A pair of diastereoisomeric C-glucofuranosyl flavones from the flowers of Gypsophila oldhamiana

Nat Prod Res. 2023 Sep 26:1-5. doi: 10.1080/14786419.2023.2261138. Online ahead of print.

Abstract

Two new C-glucofuranosyl flavones apigenin 6-C-β-glucofuranoside (1) and apigenin 6-C-α-glucofuranoside (2) together with four known compounds (3-6) were isolated from the flowers of Gypsophila oldhamiana. Their structures were elucidated on the basis of extensive spectroscopic analyses. These compounds were evaluated for the cytotoxic activities against four human cancer cell lines and did not exhibit any significant bioactivities (IC50 values > 10 μM).

Keywords: C-glucofuranoside; Gypsophila oldhamiana; cytotoxic activity; flavone.