Myeloid/lymphoid neoplasm with a novel cryptic RBPMS::FGFR1 rearrangement presenting as de novo acute leukemias

Tianyu Yang; Nayyara Mahmood; Bradley Goldberg; Johnny Cevallos; Peihong Hsu; Jonathan Kolitz; Ninette Cohen; Xinmin Zhang

doi:10.1080/10428194.2023.2262640

Myeloid/lymphoid neoplasm with a novel cryptic RBPMS::FGFR1 rearrangement presenting as de novo acute leukemias

Leuk Lymphoma. 2023 Dec;64(14):2338-2342. doi: 10.1080/10428194.2023.2262640. Epub 2023 Dec 25.

Authors

Tianyu Yang^{1

2}, Nayyara Mahmood^{1

2}, Bradley Goldberg^{1

3}, Johnny Cevallos^{1

2}, Peihong Hsu^{1

2}, Jonathan Kolitz^{1

3}, Ninette Cohen^{1

2}, Xinmin Zhang^{1

2}

Affiliations

¹ Northwell Health, Greenvale, NY, USA.
² Department of Pathology and Laboratory Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Greenvale, NY, USA.
³ Zuckerberg Cancer Center, Department of Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Greenvale, NY, USA.

PMID: 37791611
DOI: 10.1080/10428194.2023.2262640

No abstract available

Keywords: 8p11 myeloproliferative syndrome (EMS); Fibroblast growth factor receptor 1 (FGFR1); Myeloid/lymphoid neoplasm with FGFR1 rearrangement (M/LNFGFR1); RBPMS::FGFR1 fusion; RNA binding protein multiple splicing (RBPMS).

Publication types

Case Reports

MeSH terms

Chromosomes, Human, Pair 8
Humans
Leukemia* / diagnosis
Leukemia* / genetics
Myeloproliferative Disorders* / diagnosis
Myeloproliferative Disorders* / genetics
RNA-Binding Proteins
Receptor, Fibroblast Growth Factor, Type 1 / genetics
Translocation, Genetic

Substances

FGFR1 protein, human
RBPMS protein, human
Receptor, Fibroblast Growth Factor, Type 1
RNA-Binding Proteins