Antiaging Effects of Topical Defensins

Arman Danielian; Marie Danielian; Melodyanne Y Cheng; Jason Burton; Peter S Han; Rhorie P R Kerr

doi:10.1016/j.fsc.2023.05.010

Antiaging Effects of Topical Defensins

Facial Plast Surg Clin North Am. 2023 Nov;31(4):535-546. doi: 10.1016/j.fsc.2023.05.010. Epub 2023 Jul 26.

Authors

Arman Danielian¹, Marie Danielian², Melodyanne Y Cheng³, Jason Burton⁴, Peter S Han¹, Rhorie P R Kerr⁵

Affiliations

¹ Department of Head and Neck Surgery, David Geffen School of Medicine at UCLA, 200 Medical Plaza, Suite 550, Los Angeles, CA 90095, USA.
² Independent Researcher, 200 Medical Plaza, Suite 550, Los Angeles, CA 90095, USA.
³ David Geffen School of Medicine at UCLA, 10833 Le Conte Ave, Los Angeles, CA 90095, USA.
⁴ University of California Los Angeles, 200 Medical Plaza, Suite 550, Los Angeles, CA 90095, USA.
⁵ Department of Head and Neck Surgery, David Geffen School of Medicine at UCLA, 200 Medical Plaza, Suite 550, Los Angeles, CA 90095, USA. Electronic address: rkerr@mednet.ucla.edu.

PMID: 37806687
DOI: 10.1016/j.fsc.2023.05.010

Abstract

Topical defensins have recently gained attention as agents to improve skin composition. This study aimed to aggregate and synthesize studies in the literature assessing the effects of topical defensins on skin composition in the context of its ability to combat signs of aging.

Keywords: Aesthetics; Defensins; Dermatology; LGR6+ stem cells; Rhytids; Skin aging.

Publication types

Review

MeSH terms

Defensins
Humans
Skin Aging*
Skin*

Substances

Defensins