Invasive Group A Streptococcus in Infants Less Than 1-year of Age From 2012 to 2022: A Single-Center Experience

J Pediatric Infect Dis Soc. 2024 Jan 29;13(1):110-113. doi: 10.1093/jpids/piad105.

Abstract

The incidence of invasive Group A Streptococcus (iGAS) has varied throughout the COVID-19 pandemic. We reviewed iGAS infections in infants ≤1 year from 2012 to 2022. Twenty-five percent of cases occurred in the last quarter of 2022. Pneumonia (21.8%) was the most common presentation. Twenty-one patients (65.6%) were successfully transitioned to oral antibiotics.

Keywords: Streptococcus pyogenes; GAS; infant; invasive infection; pediatric.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Humans
  • Incidence
  • Infant
  • Pandemics*
  • Streptococcal Infections* / drug therapy
  • Streptococcal Infections* / epidemiology
  • Streptococcus pyogenes

Substances

  • Anti-Bacterial Agents