Preoperative Metal Allergy Testing for Pectus Excavatum Repair Does Not Effectively Identify Patients Who Develop Metal bar Allergy

J Pediatr Surg. 2024 May;59(5):956-961. doi: 10.1016/j.jpedsurg.2023.10.068. Epub 2023 Nov 2.

Abstract

Background: Metal allergy following placement of a metal pectus bar for minimally invasive repair of pectus excavatum (MIRPE) is a rare complication with potentially significant morbidity. There is no consensus regarding preoperative metal allergy testing (MAT). This study aims to assess incidence of metal allergy and titanium bar use in tested and untested patients and trends in MAT with different approaches to MAT.

Methods: A retrospective chart review was performed on patients who underwent MIRPE from July 2009 to June 2022 at a single institution. During this time, MAT was performed routinely (RT; routine testing) and selectively (ST; selective testing).

Results: The cohort included 741 patients for analysis. Metal bar allergy was documented in 1.3 % of all patients; the incidence was 1.3 % in patients with MAT and 1.4 % without MAT. The incidence of bar allergy was 1.1 % in the RT group and 1.6 % in the ST group. In the RT group, bar allergy occurred in 1.4 % (3/216) of patients with a negative MAT. In the ST group, bar allergy occurred in 1.2 % (2/164) of patients with a negative MAT and in 1.9 % (3/162) of untested patients with a stainless-steel bar. Titanium bar use was not significantly different between the RT and ST groups (18.3 % vs 16.3 %, p > 0.05).

Conclusion: The incidence of metal bar allergy after MIRPE was less than 2 %, and titanium bar use was not significantly different in routine and selective testing groups. MAT was not associated with a reduction in bar allergy, and its use remains unsupported.

Level of evidence: III.

Keywords: Metal allergy; Metal implant; Minimally invasive repair of pectus excavatum; Nuss procedure; Pectus excavatum; Skin patch test.

MeSH terms

  • Funnel Chest* / complications
  • Funnel Chest* / surgery
  • Humans
  • Hypersensitivity* / diagnosis
  • Hypersensitivity* / epidemiology
  • Hypersensitivity* / etiology
  • Minimally Invasive Surgical Procedures / adverse effects
  • Plastic Surgery Procedures*
  • Retrospective Studies
  • Titanium / adverse effects
  • Treatment Outcome

Substances

  • Titanium