The Epidemiologic and Clinical Characteristics of the 2023 Dengue Outbreak in Bangladesh

Open Forum Infect Dis. 2024 Feb 2;11(2):ofae066. doi: 10.1093/ofid/ofae066. eCollection 2024 Feb.

Abstract

The ongoing 2023 dengue outbreak is the worst ever case reported in Bangladesh. There is a lack of epidemiological studies on the outbreak. A 2-tailed t test was performed. Multivariable logistic regression analysis was conducted. We found about 277 801 cases and 1393 deaths from the 2023 dengue outbreak. About 52% of the cases were from outside of Dhaka. The male:female ratio was about 3:2. The highest frequency of cases was found among people aged 19-29 years (28.7%, 79 673 of 277 801; P = .001). The overall case fatality rate (CFR) was 0.5%. The highest CFR was found among children aged 0-10 years (12%). Fever (99%) was the most prevalent, followed by joint pain (86%). We found significantly higher odds of fatalities (adjusted odds ratio [aOR], 4.21; 95% CI, 3.93-4.74; P = .05), cases (aOR, 3.85; 95% CI, 3.25-4.12; P = .001) and hospitalizations (aOR, 3.26; 95% CI, 3.11-4.04; P = .006) during the 2023 outbreak compared with previous outbreaks during 2008-2022. This is one of the early reports of epidemiological and clinical characteristics of ongoing dengue outbreak.

Keywords: Bangladesh; clinical characteristics; dengue; epidemiology; outbreak.